Bethan Lewis is set to lead the side out at Affidea Stadium, with Kate Williams ruled out of the rest of the tournament with a leg injury.
Catherine Richards has also joined fellow wing Lisa Neumann on the sidelines after suffering a serious knee injury against the Red Roses.
The tournament returns this weekend after a two-week hiatus, with Wales looking to pick up their first win of the campaign.
They are currently bottom of the table, but have two bonus points, which could prove crucial in their bid to avoid a third consecutive wooden spoon.
Ireland are fourth, with their sole victory coming over Italy, who Wales host at Cardiff Arms Park in the final round on Sunday, 17 May.
“I’m happy with the small wins against England, obviously we were disappointed with leaking 60 points, however set-piece and getting the try bonus point was very good for us,” said Lynn.
“Ireland will be upset as a group, they threw everything at France and came away with nothing, they’re going to be hurt and wounded and are really going to be targeting us.
“It’s all about making sure that we can back up everything we did well against England and everything we want to be putting right against Ireland.”
